2021.09.18 (20h30) - Arouca 2-2 Vitoria Guimaraes
2021.09.18 (20h00) - Alaves 0-2 Osasuna
2021.09.18 (19h45) - Salernitana 0-1 Atalanta
2021.09.18 (18h00) - Belenenses 1-1 Gil Vicente
2021.09.18 (17h30) - FC Koln 1-1 RB Leipzig
2021.09.18 (17h30) - Elche 1-1 Levante
2021.09.18 (17h30) - Aston Villa 3-0 Everton
2021.09.18 (17h00) - Inter 6-1 Bologna
2021.09.18 (15h15) - Atl. Madrid 0-0 Ath Bilbao
2021.09.18 (15h00) - Manchester City 0-0 Southampton
2021.09.18 (15h00) - Liverpool 3-0 Crystal Palace
2021.09.18 (14h30) - Mainz 0-0 Freiburg
2021.09.18 (14h30) - Bayern Munich 7-0 Bochum
2021.09.18 (14h30) - Augsburg 1-0 B. Monchengladbach
2021.09.18 (14h30) - Arminia Bielefeld 0-0 Hoffenheim
2021.09.18 (14h00) - Genoa 1-2 Fiorentina
2021.09.18 (13h00) - Rayo Vallecano 3-0 Getafe
2021.09.18 (12h30) - Wolves 0-2 Brentford
2021.09.17 (20h15) - Portimonense 2-1 Santa Clara
2021.09.17 (20h00) - Newcastle 1-1 Leeds
2021.09.17 (20h00) - Celta Vigo 1-2 Cadiz CF
2021.09.17 (19h45) - Sassuolo 0-1 Torino
2021.09.17 (19h30) - Hertha Berlin 2-1 Greuther Furth
2021.09.16 (20h00) - Rangers 0-2 Lyon
2021.09.16 (20h00) - Leicester 2-2 Napoli
2021.09.16 (17h45) - Qarabag 0-0 Basel (Europa Conference League)
2021.09.16 (17h45) - Midtjylland 1-1 Ludogorets
2021.09.16 (17h45) - Lokomotiv Moscow 1-1 Marseille
2021.09.16 (17h45) - Galatasaray 1-0 Lazio
2021.09.16 (17h45) - Crvena zvezda 2-1 Braga
2021.09.16 (17h45) - Betis 4-3 Celtic
2021.09.16 (17h45) - Bayer Leverkusen 2-1 Ferencvaros
2021.09.15 (20h00) - Sporting 1-5 Ajax
2021.09.15 (20h00) - Manchester City 6-3 RB Leipzig
2021.09.15 (20h00) - Liverpool 3-2 AC Milan
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